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Journal Article 4

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2018 1

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Agent-based simulation 1

Complexity 1

Coordination 1

Distributed search 1

L-trp-NCA 1

NK landscapes 1

adoptive transfer 1

antiviral in the greenhouse 1

antiviral plant protectant 1

antiviral plant protectant / antiviral in the greenhouse / field evaluation / l-trp-NCA / synthesis optimization / toxicity tests 1

field evaluation 1

genetic modification 1

immune checkpoint inhibitor 1

immunotherapy 1

natural killer cells 1

synthesis optimization 1

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Organizational dynamics in adaptive distributed search processes: effects on performance and the role of complexity

Friederike WALL

Frontiers of Information Technology & Electronic Engineering 2016, Volume 17, Issue 4, Pages 283-295 doi: 10.1631/FITEE.1500306

Abstract: Employing an agent-based simulation based on the framework of NK landscapes we analyze different temporal

Keywords： Agent-based simulation Complexity Coordination Distributed search NK landscapes

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Challenges of NK cell-based immunotherapy in the new era

Fang Fang, Weihua Xiao, Zhigang Tian

Frontiers of Medicine 2018, Volume 12, Issue 4, Pages 440-450 doi: tzg@ustc.edu.cn

Abstract: Various cellular sources, including peripheral blood mononuclear cells (PBMCs), stem cells, and NK celllines, have been used for producing NK cells.In particular, NK cells that expanded from allogeneic PBMCs exhibit better efficacy than those that didactivities, and reliability of the cell products, researchers must develop an optimal protocol for producing NKIn this review, the challenges on NK cell-based therapeutic approaches and clinical outcomes are discussed

Keywords： natural killer cells immunotherapy adoptive transfer genetic modification immune checkpoint inhibitor

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ROUTE DEVELOPMENT, ANTIVIRAL STUDIES, FIELD EVALUATION AND TOXICITY OF AN ANTIVIRAL PLANT PROTECTANT NK0238

Frontiers of Agricultural Science and Engineering 2022, Volume 9, Issue 1, doi: 10.15302/J-FASE- 2021390

Abstract: Further exploration of this led to the identification of NK0238 as a highly effective agent for the preventiontriphosgene to produce l-tryptophan-N-carboxylic anhydride, which then reacts with n-octylamine to give NK0238In addition, the route was used for the preparation of NK0238 on a>40 g scale permitting further assessmentNK0238 exhibited useful antiviral activities against a variety of viruses both in greenhouse and fieldThe toxicity tests showed that NK0238 was not acutely toxic to birds, fish, honey bees and silkworms.

Keywords： antiviral plant protectant / antiviral in the greenhouse / field evaluation / l-trp-NCA / synthesis optimization / toxicity tests

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ROUTE DEVELOPMENT, ANTIVIRAL STUDIES, FIELD EVALUATION AND TOXICITY OF AN ANTIVIRAL PLANT PROTECTANT NK0238

Wentao XU, Hao TIAN, Hongjian SONG, Yuxiu LIU, Yongqiang LI, Qingmin WANG

Frontiers of Agricultural Science and Engineering Pages 110-119 doi: 10.15302/J-FASE-2021390

Abstract: Further exploration of this led to the identification of NK0238 as a highly effective agent for the preventiontriphosgene to produce L-tryptophan- -carboxylic anhydride, which then reacts with -octylamine to give NK0238In addition, the route was used for the preparation of NK0238 on a > 40 g scale permitting further assessmentNK0238 exhibited useful antiviral activities against a variety of viruses both in greenhouse and fieldThe toxicity tests showed that NK0238 was not acutely toxic to birds, fish, honey bees and silkworms.

Keywords： antiviral plant protectant antiviral in the greenhouse field evaluation L-trp-NCA synthesis optimization toxicity tests